Amniotic Tissue Platform
PLACENTAL TISSUES • AN IDEAL SOURCE FOR HUMAN ECM ALLOGRAFTS
Amniotic membranes and placental tissues are increasingly being used in a wide range of surgical applications, including general surgery,[1,2] corneal,[3-5] plastic surgery, burns and wounds,[7-13] sports medicine,[14-16] foot and ankle, spine and dura,[18-20] and nerve wrapping or dural covering[21-24] procedures.
These tissues provide a range of clinical benefits over other advanced wound care coverings and surgical biologic products, as they are shown to be immune privileged, without risk of graft failure or rejection which can lead to fibrosis;[25-28] provide an effective vapor barrier and gliding capability over the wound;[29,30] contain a high concentration of collagens, providing an effective biomechanical scaffold;[31-34] contain various growth factors, connective proteins, and TIMPs;[32,34-39] limit inflammation;[40-42] and reduce the likelihood of scar tissue formation.[32,43-45]
References on file.